Pular para o conteúdo
Merck

CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1

Sinônimos:
CPN1, CYP11B, FHI, P450C11
Espécies:
Human CYP11B1 (1584), Mouse Cyp11b1 (110115), Rat Cyp11b1 (500892), sheep CYP11B1 (767576), cow CYP11B1 (282422), domestic guinea pig Cyp11b1 (100135511)
ID UniProtKB:
P15538, Q14095, Q4VAQ8, Q4VAQ9, Q9UML2
ID do gene:
  • Human(1584) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(110115) cytochrome P450, family 11, subfamily b, polypeptide 1
  • Rat(500892) cytochrome P450, family 11, subfamily b, polypeptide 1
  • sheep(767576) cytochrome P450, family 11, subfamily B, polypeptide 1
  • cow(282422) cytochrome P450, subfamily XI B, polypeptide 1
  • domestic guinea pig(100135511) cytochrome P450, family 11, subfamily b, polypeptide 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
MABS502
Anticorpo antiCYP11B1, clone 80-7, clone 80-7, from rat,
Reatividade de espécies
human, rat
Aplicação
immunohistochemistry
western blot
HPA056348
Anti-CYP11B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
MAB6020
Anti-Cytochrome P450 11β-Hydroxylase Antibody, clone 11B2-1A4, culture supernatant, clone 11B2-1A4, Chemicon®,
Reatividade de espécies
rat
Aplicação
immunohistochemistry
western blot
SAB1303151
ANTI-CYP11B1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
flow cytometry
immunohistochemistry
western blot
ZRB2564
Anti-CYP11B1 Antibody, clone 1J14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, monkey
Aplicação
affinity binding assay
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
K1003
Ketoconazole, 99.0-101.0% (EP, titration),
Espécies
mouse, human, rat

esiRNA

Número do produto
Descrição
Espécies
EHU140441
MISSION® esiRNA, targeting human CYP11B1,
Espécies
human