CMA1
chymase 1, mast cell
Sinônimos:
CYH, MCT1, chymase
Espécies:
Human CMA1 (1215), Mouse Cma1 (17228), Rat Cma1 (25627), dog CMA1 (490628), domestic guinea pig Cma1 (100135503), naked mole-rat Cma1 (101714600), domestic cat CMA1 (101084796), sheep CMA1 (100144428)
ID UniProtKB:
ID do gene:
- Human(1215) Summary: This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008]
- Mouse(17228) chymase 1, mast cell
- Rat(25627) chymase 1, mast cell
- dog(490628) chymase 1, mast cell
- domestic guinea pig(100135503) chymase 1, mast cell
- naked mole-rat(101714600) chymase 1, mast cell
- domestic cat(101084796) chymase 1, mast cell
- sheep(100144428) chymase 1, mast cell
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Chymase Antibody, clone B7, clone B7, 2.4 mg/mL, Chemicon®,
Reatividade de espécies
human
Aplicação
dot blot
immunohistochemistry
immunohistochemistry
Anti-CMA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-Mast Cell Chymase (CMA1) antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-CMA1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Chymase Antibody, clone B7, biotin conjugated, clone B7, Chemicon®, from mouse,
Reatividade de espécies
human
Aplicação
dot blot
immunohistochemistry
immunohistochemistry
Proteins
Número do produto
Descrição
Espécies
esiRNA
Número do produto
Descrição
Espécies