Pular para o conteúdo
Merck

CHRM1

cholinergic receptor, muscarinic 1

Sinônimos:
HM1, M1, M1R
Espécies:
Human CHRM1 (1128), Mouse Chrm1 (12669), Rat Chrm1 (25229), domestic guinea pig Chrm1 (100728041), domestic cat CHRM1 (493664), domestic cat CHRM1 (101093801), dog CHRM1 (483776), sheep CHRM1 (101117029), cow CHRM1 (281684), Horse CHRM1 (100064117)
ID UniProtKB:
P11229
ID do gene:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Número do produto
Descrição
Espécies
PHL80370
Pilocarpina, phyproof® Reference Substance,
Espécies
human
PHR1493
Pilocarpina, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
P0597
Pilocarpine nitrate, meets USP testing specifications,
Espécies
human
PHR1494
Pilocarpine Nitrate, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
P1650000
Pilocarpina, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
197602
Quinuclidine, 97%,
Espécies
rat
E5406
Ethopropazine hydrochloride, ≥98% (HPLC), powder,
Espécies
human
P7412
Pirenzepine dihydrochloride, ≥98% (TLC), powder,
Espécies
human
SML0847
Benztropine mesylate, ≥98% (HPLC),
Espécies
human
P3794
Procyclidine hydrochloride, ,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA014101
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
AB5164
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
SAB4500244
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
M9808
Anti-Muscarinic Acetylcholine Receptor (M1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
51330
Harmaline, ≥95%,
Espécies
human, rat

Small Molecule - Ligand

Número do produto
Descrição
Espécies
A138
Aminobenztropine, solid,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
HTS044M
ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU009821
MISSION® esiRNA, targeting human CHRM1,
Espécies
human