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Merck

ANK3

ankyrin 3, node of Ranvier (ankyrin G)

Sinônimos:
ANKYRIN-G
Espécies:
ID UniProtKB:
ID do gene:
  • Human(288) Summary: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(11735) ankyrin 3, epithelial
  • Rat(361833) ankyrin 3, node of Ranvier (ankyrin G)
  • naked mole-rat(101719656) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic guinea pig(100734552) ankyrin 3, node of Ranvier (ankyrin G)
  • sheep(101120296) ankyrin 3, node of Ranvier (ankyrin G)
  • chicken(396309) ankyrin 3, node of Ranvier (ankyrin G)
  • Horse(100062775) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic cat(101097842) ankyrin 3, node of Ranvier (ankyrin G)
  • dog(479215) ankyrin 3, node of Ranvier (ankyrin G)
  • cow(511203) ankyrin 3, node of Ranvier (ankyrin G)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Ankyrin-G Antibody, clone N106/36, clone N106/36, from mouse,
Reatividade de espécies
rat
Aplicação
immunohistochemistry
Anti-ANK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
Anti-Ankyrin-G Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
affinity binding assay
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Ankyrin G antibody produced in mouse, clone S106-20, purified immunoglobulin,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Anti-ANK3 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunohistochemistry

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Ank3,
Espécies
mouse
MISSION® esiRNA, targeting human ANK3,
Espécies
human