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Rhenium-188 and copper-67 radiopharmaceuticals for the treatment of bladder cancer.

Rhenium-188 and copper-67 radiopharmaceuticals for the treatment of bladder cancer.

Mini reviews in medicinal chemistry (2004-02-03)

Malcolm Frier

ABSTRACT

The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular administration of Cu-67 or Re-188 radiopharmaceuticals in the treatment of bladder cancer offers some promise for improvement in this situation.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Rhenium, powder, 99.995% trace metals basis

Sigma-Aldrich

Rhenium, powder, −100 mesh, ≥99.9% trace metals basis

Sigma-Aldrich

Rhenium, foil, thickness 0.25 mm, 99.98% trace metals basis

Rhenium, wire reel, 0.2m, diameter 0.3mm, annealed, 99.97%

Rhenium, wire reel, 0.5m, diameter 0.3mm, annealed, 99.97%

Rhenium, wire reel, 2m, diameter 0.125mm, annealed, 99.97%

Rhenium, wire reel, 2m, diameter 0.15mm, annealed, 99.97%

Rhenium, wire reel, 0.1m, diameter 0.076mm, annealed, 99.97%

Rhenium, wire reel, 1m, diameter 0.076mm, annealed, 99.97%

Rhenium, wire reel, 0.2m, diameter 1.0mm, annealed, 99.97%

Rhenium, wire reel, 0.025m, diameter 1.0mm, annealed, 99.97%

Rhenium, wire reel, 2m, diameter 0.25mm, annealed, 99.97%

Rhenium, wire reel, 0.5m, diameter 0.10mm, annealed, 99.97%

Rhenium, wire reel, 0.1m, diameter 0.3mm, annealed, 99.97%

Rhenium, wire reel, 1m, diameter 0.125mm, annealed, 99.97%

Rhenium, wire reel, 0.2m, diameter 0.076mm, annealed, 99.97%

Rhenium, wire reel, 0.2m, diameter 0.125mm, annealed, 99.97%

Rhenium, wire reel, 0.05m, diameter 0.5mm, annealed, 99.97%

Rhenium, wire reel, 0.5m, diameter 0.125mm, annealed, 99.97%

Rhenium, wire reel, 0.1m, diameter 0.15mm, annealed, 99.97%

Rhenium, wire reel, 0.1m, diameter 0.5mm, annealed, 99.97%

Rhenium, wire reel, 1m, diameter 0.15mm, annealed, 99.97%

Rhenium, wire reel, 0.2m, diameter 0.15mm, annealed, 99.97%

Rhenium, wire reel, 0.2m, diameter 0.5mm, annealed, 99.97%

Rhenium, wire reel, 0.05m, diameter 1.0mm, annealed, 99.97%

Rhenium, wire reel, 0.5m, diameter 0.5mm, annealed, 99.97%

Rhenium, wire reel, 0.5m, diameter 0.15mm, annealed, 99.97%

Rhenium, wire reel, 0.2m, diameter 0.178mm, annealed, 99.97%

Rhenium, wire reel, 1m, diameter 0.178mm, annealed, 99.97%

Rhenium, wire reel, 2m, diameter 0.2mm, annealed, 99.97%