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  • Biological-like vesicular structures self-assembled from DNA-block copolymers.

Biological-like vesicular structures self-assembled from DNA-block copolymers.

Chemical communications (Cambridge, England) (2012-02-02)
Nicolas Cottenye, Marie-Isabel Syga, Sergey Nosov, Axel H E Müller, Lydie Ploux, Corinne Vebert-Nardin
ABSTRACT

The polymer modification of short nucleotide sequences has been achieved for future use as self-assembled biologically active structures with sizes in the nanometre range. Co-assembly of the resulting DNA-based amphiphilic block copolymers with native proteins demonstrates the self-assembly of biological-like vesicular structures.