SAB4300262

Anti-phospho-CFL1 (pTyr¹³⁹) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CFL antibody produced in rabbit, Anti-cofilin 1 (non-muscle) antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~19 kDa
• species reactivity: rat, human, mouse
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• isotype: IgG
• immunogen sequence: (N-C-YP-E-E)
• NCBI accession no.: NP_005498.1
• UniProt accession no.: P23528
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr139)
• Gene Information: human ... CFL1(1072)

Description

Immunogen

Peptide sequence around phosphorylation site of tyrosine 139 (N-C-Y(p)-E-E), according to the protein CFL1.

Features and Benefits

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Target description

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable