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8.53026

Sigma-Aldrich

Boc-Hyp-OH (cryst)

Novabiochem®

Synonym(s):

Boc-Hyp-OH (cryst), N-α-t.-Boc-L-trans-4-hydroxyproline

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About This Item

Empirical Formula (Hill Notation):
C10H17NO5
CAS Number:
Molecular Weight:
231.25
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥97% (TLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

122 °C (decomposition)

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

InChI

1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)

InChI key

BENKAPCDIOILGV-UHFFFAOYSA-N

General description

Building block for introduction of hydroxyproline amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Linkage

Replaces: 04-12-0104

Analysis Note

Color (visual): white to slight yellow to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -71.5 - -64.5 °
Purity (TLC(0110)): ≥ 97 %
Purity (TLC(CMA2)): ≥ 97 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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