RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
Synonyms:
RIB1, RNS1
Species:
Human RNASE1 (6035), Mouse Rnase1 (19752), Rat Rnase1 (364304), domestic cat RNASE1 (101082663), dog RNASE1 (475395), naked mole-rat Rnase1 (101706346), cow RNASE1 (280930), cow RNASE1 (282340), sheep RNASE1 (101113761), fruit fly Rnase1 (5656971)
UniProtKB ID:
Gene ID:
- Human(6035) Summary: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
- Mouse(19752) ribonuclease, RNase A family, 1 (pancreatic)
- Rat(364304) ribonuclease, RNase A family, 1 (pancreatic)
- domestic cat(101082663) ribonuclease, RNase A family, 1 (pancreatic)
- dog(475395) ribonuclease, RNase A family, 1 (pancreatic)
- naked mole-rat(101706346) ribonuclease, RNase A family, 1 (pancreatic)
- cow(280930) ribonuclease, RNase A family, 1 (pancreatic)
- cow(282340) ribonuclease, RNase A family, 1 (pancreatic)
- sheep(101113761) ribonuclease, RNase A family, 1 (pancreatic)
- fruit fly(5656971) Ribonuclease 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RNASE1 (34-46) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Monoclonal Anti-RNASE1 antibody produced in mouse, clone 1E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
esiRNA
Product Number
Description
Species