PMCH
pro-melanin-concentrating hormone
Synonyms:
MCH
Species:
Human PMCH (5367), Mouse Pmch (110312), Rat Pmch (24659), chicken PMCH (418091), Zebrafish pmch (100003610), domestic guinea pig Pmch (100718615), naked mole-rat Pmch (101708626), domestic cat PMCH (101100983), dog PMCH (449022), sheep PMCH (443522)
UniProtKB ID:
Gene ID:
- Human(5367) Summary: The melanin-concentrating hormone (MCH) is a cyclic neuropeptide isolated initially from salmon pituitary gland and later from rat hypothalamus. In mammals, MCH perikarya are confined largely to the lateral hypothalamus and zona incerta area with extensive neuronal projections throughout the brain, including the neurohypophysis. The anatomic distribution suggests a neurotransmitter or neuromodulator role for MCH in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. MCH and 2 other putative neuropeptides, NEI and NGE, are encoded by the same precursor and appear colocalized in nerve cells and in many instances within the projections. The precursor is designated pro-melanin-concentrating hormone (PMCH) (summary by Nahon et al., 1992 [PubMed 1572663]
- Mouse(110312) pro-melanin-concentrating hormone
- Rat(24659) pro-melanin-concentrating hormone
- chicken(418091) pro-melanin-concentrating hormone
- Zebrafish(100003610) pro-melanin concentrating hormone
- domestic guinea pig(100718615) pro-melanin-concentrating hormone
- naked mole-rat(101708626) pro-melanin-concentrating hormone
- domestic cat(101100983) pro-melanin-concentrating hormone
- dog(449022) pro-melanin-concentrating hormone
- sheep(443522) pro-melanin-concentrating hormone
- cow(508013) pro-melanin-concentrating hormone
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PMCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
Monoclonal Anti-PMCH antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-MCH antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
microarray
microarray
Anti-PMCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry