P2RY12
purinergic receptor P2Y, G-protein coupled, 12
Synonyms:
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Species:
Human P2RY12 (64805), Mouse P2ry12 (70839), Rat P2ry12 (64803), dog P2RY12 (442958), cow P2RY12 (408007), sheep P2RY12 (101117897), naked mole-rat P2ry12 (101701294), domestic cat P2RY12 (101094044), domestic guinea pig P2ry12 (100720551)
UniProtKB ID:
Gene ID:
- Human(64805) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
- Mouse(70839) purinergic receptor P2Y, G-protein coupled 12
- Rat(64803) purinergic receptor P2Y, G-protein coupled, 12
- dog(442958) purinergic receptor P2Y, G-protein coupled, 12
- cow(408007) purinergic receptor P2Y, G-protein coupled, 12
- sheep(101117897) purinergic receptor P2Y, G-protein coupled, 12
- naked mole-rat(101701294) purinergic receptor P2Y, G-protein coupled, 12
- domestic cat(101094044) purinergic receptor P2Y, G-protein coupled, 12
- domestic guinea pig(100720551) purinergic receptor P2Y, G-protein coupled, 12
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Small Molecule - Agonist
Product Number
Description
Species
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Small Molecule - Antagonist
Product Number
Description
Species
Clopidogrel Bisulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Prasugrel for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-P2RY12 Antibody, clone 2C12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-P2Y12 Receptor, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-P2RY12 Antibody, clone 10B5.3.27, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot