MBD3
methyl-CpG binding domain protein 3
Synonyms:
Species:
Human MBD3 (53615), Mouse Mbd3 (17192), Rat Mbd3 (362834), domestic cat MBD3 (101098692), Thale Cress MBD3 (828069), chicken MBD3 (770153), dog MBD3 (485080), sheep MBD3 (101119469), naked mole-rat Mbd3 (101696358), cow MBD3 (616090)
UniProtKB ID:
Gene ID:
- Human(53615) Summary: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq, Jul 2008]
- Mouse(17192) methyl-CpG binding domain protein 3
- Rat(362834) methyl-CpG binding domain protein 3
- domestic cat(101098692) methyl-CpG binding domain protein 3
- Thale Cress(828069) methyl-CpG-binding domain-containing protein 3
- chicken(770153) methyl-CpG binding domain protein 3
- dog(485080) methyl-CpG binding domain protein 3
- sheep(101119469) methyl-CpG binding domain protein 3
- naked mole-rat(101696358) methyl-CpG binding domain protein 3
- cow(616090) methyl-CpG binding domain protein 3
- domestic guinea pig(100713224) methyl-CpG binding domain protein 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MBD3 Antibody, clone 1K19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-MBD3 antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot