MAP3K14
mitogen-activated protein kinase kinase kinase 14
Synonyms:
FTDCR1B, HS, HSNIK, NIK
Species:
Human MAP3K14 (9020), Mouse Map3k14 (53859), Rat Map3k14 (360640), dog MAP3K14 (490926), chicken MAP3K14 (419964), sheep MAP3K14 (101118799), Domestic Rabbit MAP3K14 (100351032), cow MAP3K14 (508367), Horse MAP3K14 (100050140), naked mole-rat Map3k14 (101703313) ...More
UniProtKB ID:
Gene ID:
- Human(9020) Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
- Mouse(53859) mitogen-activated protein kinase kinase kinase 14
- Rat(360640) mitogen-activated protein kinase kinase kinase 14
- dog(490926) mitogen-activated protein kinase kinase kinase 14
- chicken(419964) mitogen-activated protein kinase kinase kinase 14
- sheep(101118799) mitogen-activated protein kinase kinase kinase 14
- Domestic Rabbit(100351032) mitogen-activated protein kinase kinase kinase 14
- cow(508367) mitogen-activated protein kinase kinase kinase 14
- Horse(100050140) mitogen-activated protein kinase kinase kinase 14
- naked mole-rat(101703313) mitogen-activated protein kinase kinase kinase 14
- domestic guinea pig(100719582) mitogen-activated protein kinase kinase kinase 14
- domestic cat(101083468) mitogen-activated protein kinase kinase kinase 14
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Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-NIK (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-MAP3K14 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit
Application
western blot
Anti-MAP3K14 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-NIK Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
MAP3K14(NIK) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human