Skip to Content
Merck

IL6

interleukin 6 (interferon, beta 2)

Synonyms:
BSF2, HGF, HSF, IFNB2, IL-6
Species:
UniProtKB ID:
Gene ID:
  • Human(3569) Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
  • Mouse(16193) interleukin 6
  • Rat(24498) interleukin 6
  • Zebrafish(100885851) interleukin 6 (interferon, beta 2)
  • chicken(395337) interleukin 6 (interferon, beta 2)
  • dog(403985) interleukin 6 (interferon, beta 2)
  • domestic cat(493687) interleukin 6 (interferon, beta 2)
  • Horse(100034196) interleukin 6 (interferon, beta 2)
  • cow(517016) interleukin 6 (interferon, beta 2)
  • cow(280826) interleukin 6 (interferon, beta 2)
  • Goat(100860785) interleukin 6 (interferon, beta 2)
  • sheep(443406) interleukin 6 (interferon, beta 2)
  • Domestic Rabbit(100008733) interleukin 6 (interferon, beta 2)
  • naked mole-rat(101702602) interleukin 6 (interferon, beta 2)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Rhesus Macaque IL6 / Interleukin-6 ELISA Kit, ,
Species
Rat IL-6 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
rat
Rat Interleukin-6 ELISA Kit, for for cell lysate and tissue lysate,
Species
rat
Mouse IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Porcine IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
dog

Small Molecule - Antagonist

Product Number
Description
Species
Probucol, analytical standard,
Species
human
4-Hydroxytamoxifen, analytical standard, (E) and (Z) isomers (50:50),
Species
human, rat
4-Hydroxytamoxifen, ≥70% Z isomer (remainder primarily E-isomer),
Species
human, rat
(Z)-4-Hydroxytamoxifen, ≥98% Z isomer,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IL6 antibody produced in mouse, clone 6D9A1, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-Interleukin-6 Antibody, clone B-E8, clone B-E8, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

neutralization
SILuRich Anti-IL6 MAb, biotin conjugated, clone IL6-4G1, purified from hybridoma cell culture,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Anti-Interleukin-6 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-IL6 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
Interleukin-6, Human, Recombinant, E. coli, ,
Species
human
Interleukin-6, human (hIL-6), recombinant (E. coli),
Species
human
Interleukin-6 from rat, IL-6, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture,
Species
rat
IL-6 from mouse, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
mouse
Interleukin-6 human, IL-6, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il6,
Species
mouse
MISSION® esiRNA, targeting human IL6,
Species
human