HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
Synonyms:
5-HT(2B), 5-HT2B
Species:
Human HTR2B (3357), Mouse Htr2b (15559), Rat Htr2b (29581), chicken HTR2B (395581), Zebrafish htr2b (751784), dog HTR2B (403881), cow HTR2B (407135), Horse HTR2B (100057052), domestic cat HTR2B (101095762), Domestic Rabbit HTR2B (100343392) ...More
UniProtKB ID:
Gene ID:
- Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
- Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
- Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
- Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
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Description
Species
Small Molecule - Antagonist
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Description
Species
Antibodies
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Description
Species Reactivity
Application
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-HTR2B (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, pig
Application
western blot
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-HTR2B antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Small Molecule - Blocker
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Description
Species
Small Molecule - Inhibitor
Small Molecule - Ligand
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Description
Species
Small Molecule - Metabolite
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Description
Species
Small Molecule - Mixed Agonist/Antagonist
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Description
Species
Small Molecule - Precursor
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Description
Species
esiRNA
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Description
Species