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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonyms:
EPND, GluN2A, NMDAR2A, NR2A
Species:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
UniProtKB ID:
Q12879, O00669, Q17RZ6
Gene ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Product Number
Description
Species
239488
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Species
rat
D9684
Dextromethorphan hydrobromide, meets USP testing specifications,
Species
human
PHR1018
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Species
human
R1276
Reversin 121, ≥97% (HPLC), powder,
Species
mouse, rat, human
A263
ATPA, solid,
Species
human, rat

Small Molecule - Allosteric Modulator

Product Number
Description
Species
561479
4-Aminopiperidine, ,
Species
rat
K0250
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Species
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Species
human
A78403
4-Aminopyridine, 98%,
Species
rat, human, mouse

Small Molecule - Antagonist

Product Number
Description
Species
G8898
Glycine, suitable for electrophoresis, ≥99%,
Species
rat
15527
Glycine, meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance),
Species
rat
50046
Glycine, BioUltra, for molecular biology, ≥99.0% (NT),
Species
rat
33226
Glycine, puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance),
Species
rat
410225
Glycine, ACS reagent, ≥98.5%,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
AB1555
Anti-NMDAR2A Antibody, serum, Chemicon®,
Species Reactivity
fish, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
MAB5216
Anti-NMDAR2A Antibody, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
MAB5572
Anti-NMDAR2A Antibody, ascites fluid, clone 2H9.24A6, Chemicon®,
Species Reactivity
frog, human, mouse, rabbit, rat
Application
western blot
04-901
Anti-NR2A Antibody, clone A12W, rabbit monoclonal, culture supernatant, clone A12W, Upstate®,
Species Reactivity
mouse, rat
Application
western blot
SAB5200904
Monoclonal Anti-Glun2A/Nr2A - Rpe antibody produced in mouse, clone S327-95, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Species
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
I5109
Indole-2-carboxylic acid, 98%,
Species
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
Q2128
Quisqualic acid, powder,
Species
rat
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Species
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
127027
N-Methyl-1,3-diaminopropane, 98%,
Species
rat
33262
1,3-Diamino-2-propanol, purum, ≥96.5% (GC),
Species
rat
195812
4-Amino-1-benzylpiperidine, 98%,
Species
rat
115738
4-Amino-2,2,6,6-tetramethylpiperidine, 98%,
Species
rat
227412
N,N,2,2-Tetramethyl-1,3-propanediamine, 97%,
Species
rat

esiRNA

Product Number
Description
Species
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Species
mouse
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Species
human