ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
Synonyms:
ESP1, SEPA
Species:
Human ESPL1 (9700), Mouse Espl1 (105988), Rat Espl1 (315330), chicken ESPL1 (425536), Zebrafish espl1 (797406), domestic guinea pig Espl1 (100733255), naked mole-rat Espl1 (101723260), Domestic Rabbit ESPL1 (100356105), domestic cat ESPL1 (101084118), Horse ESPL1 (100063779) ...More
UniProtKB ID:
Gene ID:
- Human(9700) Summary: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]
- Mouse(105988) extra spindle poles-like 1 (S. cerevisiae)
- Rat(315330) extra spindle pole bodies homolog 1 (S. cerevisiae)
- chicken(425536) extra spindle pole bodies homolog 1 (S. cerevisiae)
- Zebrafish(797406) extra spindle poles like 1
- domestic guinea pig(100733255) extra spindle pole bodies homolog 1 (S. cerevisiae)
- naked mole-rat(101723260) extra spindle pole bodies homolog 1 (S. cerevisiae)
- Domestic Rabbit(100356105) extra spindle pole bodies homolog 1 (S. cerevisiae)
- domestic cat(101084118) extra spindle pole bodies homolog 1 (S. cerevisiae)
- Horse(100063779) extra spindle pole bodies homolog 1 (S. cerevisiae)
- cow(506740) extra spindle pole bodies homolog 1 (S. cerevisiae)
- sheep(101105898) extra spindle pole bodies homolog 1 (S. cerevisiae)
- dog(607879) extra spindle pole bodies homolog 1 (S. cerevisiae)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SEPARASE antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-ESPL1 antibody produced in mouse, clone 6H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ESPL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry