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Merck

DEGS1

delta(4)-desaturase, sphingolipid 1

Synonyms:
DEGS, DEGS-1, DES1, Des-1, FADS7, MLD
Species:
UniProtKB ID:
Gene ID:
  • Human(8560) Summary: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
  • Mouse(13244) degenerative spermatocyte homolog 1 (Drosophila)
  • Rat(58970) delta(4)-desaturase, sphingolipid 1
  • Zebrafish(327075) degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
  • chicken(421327) degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
  • naked mole-rat(101722992) delta(4)-desaturase, sphingolipid 1
  • sheep(100192315) delta(4)-desaturase, sphingolipid 1
  • cow(507290) degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
  • domestic cat(101083993) delta(4)-desaturase, sphingolipid 1
  • dog(490395) delta(4)-desaturase, sphingolipid 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DEGS1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-DEGS1 antibody produced in mouse, clone 2E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-DEGS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-DEGS1, (C-terminal) antibody produced in mouse, clone 3F9, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DEGS1,
Species
human
MISSION® esiRNA, targeting mouse Degs1,
Species
mouse