Skip to Content
Merck

ATP1A3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

Synonyms:
AHC2, DYT12, RDP
Species:
UniProtKB ID:
Gene ID:
  • Human(478) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(232975) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Rat(24213) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic cat(101083636) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Horse(100069796) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • dog(612463) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • chicken(396467) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • naked mole-rat(101721146) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • cow(282598) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • sheep(101103751) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic guinea pig(100712985) ATPase, Na+/K+ transporting, alpha 3 polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Na+/K+ ATPase β-1 Antibody, clone C464.8, clone C464.8, Upstate®, from mouse,
Species Reactivity
bovine, canine, human, rabbit, rat
Application
immunohistochemistry
western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, clone C464.6, Upstate®, from mouse,
Species Reactivity
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 555, clone C464.6, Upstate®, from mouse,
Species Reactivity
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Application
flow cytometry
immunofluorescence

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Digitoxin for LC assay, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digoxin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Digitoxin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digitoxin, ≥92% (HPLC), powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ATP1A3,
Species
human
MISSION® esiRNA, targeting mouse Atp1a3,
Species
mouse