PHL89223

10-Hydroxy-trans-2-decenoic acid

phyproof^® Reference Substance

• Synonym(s): Royal jelly acid
• Empirical Formula (Hill Notation): C₁₀H₁₈O₃
• CAS Number: 14113-05-4
• Molecular Weight: 186.25
• MDL number: MFCD00204506
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• storage temp.: −20°C
• SMILES string: OC(/C=C/CCCCCCCO)=O
• InChI: 1S/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+
• InChI key: QHBZHVUGQROELI-SOFGYWHQSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

<ul>
<li><strong>Royal Jelly and Non-communicable Diseases:</strong> A comprehensive review on royal jelly, including its bioactive component 10-hydroxy-trans-2-decenoic acid, discusses its potential in non-communicable disease management. This study highlights the compound′s anti-inflammatory, antioxidant, and immunomodulatory effects, making it a promising candidate for novel therapeutic strategies in chronic disease management (Baptista et al., 2023).</li>
<li><strong>Dermatological Applications:</strong> Investigating the dermatological benefits of bee products, including 10-hydroxy-trans-2-decenoic acid, this review discusses the compound′s applications in skin care. It highlights its moisturizing, anti-aging, and healing properties, which are utilized in various dermatological treatments and cosmetic products (Kurek-Grecka et al., 2020).</li>
<li><strong>Glycemic Regulation:</strong> A systematic review assesses the effectiveness of royal jelly, including its active component 10-hydroxy-trans-2-decenoic acid, in glycemic regulation. The findings suggest potential benefits for diabetic patients, supporting its use as a supplementary treatment to manage blood sugar levels (Omer et al., 2019).</li>
</ul>

10-Hydroxy-trans-2-decenoic acid (10-HDA) is a component of royal jelly. It′s analysis by HPLC-UV is described in FSSAI method FSSAI 04B.031:2024

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable