V4390

VUF 8430 dihydrobromide

≥97% (NMR)

• Synonym(s): 2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester, S-(2-guanidylethyl)-isothiourea
• Empirical Formula (Hill Notation): C₄H₁₁N₅S· 2HBr
• CAS Number: 100130-32-3
• Molecular Weight: 323.05
• MDL number: MFCD01694605
• UNSPSC Code: 12352200
• PubChem Substance ID: 329829051
• NACRES: NA.77

Properties

• Assay: ≥97% (NMR)
• form: solid
• storage condition: desiccated
• solubility: deionized water: 24 mg/mL
• storage temp.: room temp
• SMILES string: Br.Br.NC(=N)NCCSC(N)=N
• InChI: 1S/C4H11N5S.2BrH/c5-3(6)9-1-2-10-4(7)8;;/h1-2H2,(H3,7,8)(H4,5,6,9);2*1H
• InChI key: GPWJSTKHQMIXCA-UHFFFAOYSA-N

Description

Biochem/physiol Actions

VUF 8430 dihydrobromide is a potent histamine H4 receptor agonist, with a 33-fold selectivity over the histamine H3 receptor and negligible affinity for the other histamine receptor.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable