I5281
L-Isoleucine
Pharma Manufacturing
Synonym(s):
(2S,3S)-2-Amino-3-methylpentanoic acid
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All Photos(2)
About This Item
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein:
1721792
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26
Recommended Products
biological source
non-animal source
Quality Level
Assay
≥98.5%
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, heavy metals, residual solvents, tested
mp
288 °C (dec.) (lit.)
solubility
1 M HCl: 50 mg/mL
application(s)
pharmaceutical (small molecule)
foreign activity
cytotoxicity, tested
SMILES string
CC[C@H](C)[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
InChI key
AGPKZVBTJJNPAG-WHFBIAKZSA-N
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General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.
Application
L-Isoleucine is an essential amino acid. It can be biosynthesized from threonine or through fermentation of carbohydrates. The amino acid L-isoleucine is an isomer of L-Leucine, differing in the position of the side chain. It is also considered to be a branched chain amino acid, along with L-Leucine and L-Valine, which are sources of fuel and/or transport during cell development. It is used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Chromatograms
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