PHR1973

Acetaminophen Impurity I

Pharmaceutical Secondary Standards; Certified Reference Material

• Synonym(s): 2′-Hydroxyacetophenone, 2-Acetylphenol
• Linear Formula: HOC₆H₄COCH₃
• CAS Number: 118-93-4
• Molecular Weight: 136.15
• Beilstein: 386123
• MDL number: MFCD00002219
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• vapor density: 4.7 (vs air)
• vapor pressure: ~0.2 mmHg ( 20 °C)
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.558 (lit.)
• bp: 213 °C/717 mmHg (lit.)
• mp: 3-6 °C (lit.)
• density: 1.133 g/mL at 20 °C; 1.131 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC(=O)c1ccccc1O
• InChI: 1S/C8H8O2/c1-6(9)7-4-2-3-5-8(7)10/h2-5,10H,1H3
• InChI key: JECYUBVRTQDVAT-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB2777 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 222.8 °F - closed cup
• Flash Point(C): 106 °C - closed cup