T1782

(+)-γ-Tocopherol

≥96% (HPLC)

• Synonym(s): gamma-Tocopherol, (R,R,R)-γ-Tocopherol, 7,8-Dimethyltocol
• Empirical Formula (Hill Notation): C₂₈H₄₈O₂
• CAS Number: 54-28-4
• Molecular Weight: 416.68
• Beilstein: 93072
• EC Number: 200-201-5
• MDL number: MFCD00066529
• UNSPSC Code: 12352211
• eCl@ss: 34058016
• PubChem Substance ID: 24899992
• NACRES: NA.79

Properties

• Assay: ≥96% (HPLC)
• form: liquid
• technique(s): HPLC: suitable
• color: dark brown; colorless to dark yellow
• storage temp.: 2-8°C
• SMILES string: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1
• InChI: 1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1
• InChI key: QUEDXNHFTDJVIY-DQCZWYHMSA-N
• Gene Information: human ... HMGCR(3156)

Description

Application

(+)-γ-Tocopherol has been used:

• as reference material for the quantification of γ-tocopherol in the oil sample using high performance liquid chromatography with diode array detector (HPLC/DAD)(192}
• as a component of diet to feed vitamin-E-depleted rats to study its effects
• as an additive in the feed to study its effects in reducing dietary induced oxidative stress in vivo and improving meat lipid stability in broilers

Biochem/physiol Actions

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble antioxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Various isofroms and analogues of tocopherol have opposing and differentiated regulatory activities in vivo.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves