sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

767484

Sigma-Aldrich

Nickel, sputtering target, diam. × thickness 2.00 in. × 0.25 in., 99.95% trace metals basis

GF06884589

Nickel, foil, 25mm disks, thickness 0.25mm, as rolled, 100%

GF57351731

Nickel, microfoil, disks, 10mm, thinness 1.0μm, specific density 895.8μg/cm², permanent mylar 3.5μm support, 99.99+%

GF10337138

Nickel, foil, not light tested, 100x100mm, thickness 0.0125mm, 99.9%

GF87457067

Nickel, foil, 2m coil, thickness 0.0075mm, 99.9%

GF09151095

Nickel, foil, not light tested, 25x25mm, thickness 0.002mm, 99.95%

GF97375832

Nickel, foil, 25x25mm, thickness 1.0mm, as rolled, 99.99+%

GF63986305

Nickel, foil, light tested, 25x25mm, thickness 0.025mm, as rolled, 100%

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

GF49702406

Nickel, foil, light tested, 50x50mm, thickness 0.0075mm, 99.95%

GF60742548

Nickel, foil, 2m coil, thickness 0.20mm, annealed, 99%

GF17268880

Nickel, foil, 150x150mm, thickness 0.3mm, annealed, 99%

GF04391591

Nickel, mesh, 100x250mm, nominal aperture 0.73mm, wire diameter 0.25mm, 26x26 wires/inch, open area 55%, plain weave mesh, 99%

GF43591934

Nickel, foil, 10mm disks, thickness 0.02mm, 99.9%

GF86630283

Nickel, foil, 0.5m coil, thickness 0.125mm, as rolled, 99.99+%

GF00494883

Nickel, foil, 10m coil, thickness 0.20mm, coil width 1mm, annealed, 99%

GF48190204

Nickel, foil, 4mm disks, thickness 0.0125mm, 99.9%

GF16048874

Nickel, microfoil, disks, 10mm, thinness 0.25μm, specific density 222.55μg/cm², permanent mylar 3.5μm support, 99.99+%

GF54355147

Nickel, wire reel, 0.2m, diameter 0.4mm, as drawn, 99.99+%

GF27065774

Nickel, foil, 10mm disks, thickness 0.038mm, 99.9%

GF95098731

Nickel, foil, 2m coil, thickness 0.3mm, coil width 1mm, annealed, 99%