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  • Does pre-coating total knee tibial implants affect the risk of aseptic revision?

Does pre-coating total knee tibial implants affect the risk of aseptic revision?

The bone & joint journal (2013-03-02)
S A Bini, Y Chen, M Khatod, E W Paxton
ABSTRACT

We evaluated the impact of pre-coating the tibial component with polymethylmethacrylate (PMMA) on implant survival in a cohort of 16 548 primary NexGen total knee replacements (TKRs) in 14 113 patients. In 13 835 TKRs a pre-coated tray was used while in 2713 TKRs the non-pre-coated version of the same tray was used. All the TKRs were performed between 2001 and 2009 and were cemented. TKRs implanted with a pre-coated tibial component had a lower cumulative survival than those with a non-pre-coated tibial component (p = 0.01). After adjusting for diagnosis, age, gender, body mass index, American Society of Anesthesiologists grade, femoral coupling design, surgeon volume and hospital volume, pre-coating was an independent risk factor for all-cause aseptic revision (hazard ratio 2.75, p = 0.006). Revision for aseptic loosening was uncommon for both pre-coated and non-pre-coated trays (rates of 0.12% and 0%, respectively). Pre-coating with PMMA does not appear to be protective of revision for this tibial tray design at short-term follow-up.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Poly(methyl methacrylate), isotactic, >80% isotactic
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 4,000
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 10,000
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 20,000
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 2,000
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 100,000
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 50,000
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 2,480,000
Sigma-Aldrich
Poly(methyl methacrylate)
Sigma-Aldrich
Poly(methyl methacrylate), average Mw ~350,000 by GPC
Sigma-Aldrich
Poly(methyl methacrylate)
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, average Mw 97,000 (Typical), average Mn 46,000 (Typical)
Sigma-Aldrich
Poly(methyl methacrylate), average Mw ~15,000 by GPC, powder
Supelco
Poly(methyl methacrylate), analytical standard, for GPC, 8,000
Sigma-Aldrich
Poly(methyl methacrylate), CP