Quinidine is an alkaloid present in the bark of the Cinchona tree. It is the D-isomer of quinine, an antimalarial drug.
Application
Quinidine sulfate salt dihydrate has been used as an antiarrhythmic drug to study its effects on phosphorylation and mutations in the cardiac sodium channel Nav1.5.
Biochem/physiol Actions
Class IA antiarrhythmic; potassium channel blocker.
Quinidine shows therapeutic effects against atrial fibrillation and cardiac arrhythmias.
Features and Benefits
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Journal of the American Heart Association, 4(4) (2015-04-15)
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