C2278

CAPSO

≥99% anhydrous basis (titration)

• Synonym(s): 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, CAPSO Free Acid
• Empirical Formula (Hill Notation): C₉H₁₉NO₄S
• CAS Number: 73463-39-5
• Molecular Weight: 237.32
• Beilstein: 5939234
• MDL number: MFCD00041778
• UNSPSC Code: 12161700
• PubChem Substance ID: 24892483
• NACRES: NA.25

Properties

• Assay: ≥99% anhydrous basis (titration)
• form: crystalline powder
• pH: 2.5-4.0
• useful pH range: 8.9-10.3
• pKa (25 °C): 9.6
• solubility: water: 0.111 g/mL, clear, colorless
• application(s): diagnostic assay manufacturing
• SMILES string: OC(CNC1CCCCC1)CS(O)(=O)=O
• InChI: 1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14)
• InChI key: INEWUCPYEUEQTN-UHFFFAOYSA-N

Description

General description

CAPSO is a useful secondary standard buffer. Second dissociation constant pK₂ value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.

Application

CAPSO was used as biological buffer in the following studies:

• To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.
• Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes. I
• Preparation of planar bilayer lipid membranes.

It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves