71790
Sodium nucleinate
Synonym(s):
Ribonucleic acid sodium salt
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About This Item
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form
powder
loss
~5% loss on drying, 20 °C (HV)
solubility
H2O: 0.1 g/mL, clear to turbid, brown-yellow (hot)
storage temp.
2-8°C
General description
Sodium nucleinate is a derivative of tetrahydrophthalazine.
Application
<ul>
<li><strong>Tetrahydrophthalazine derivative "sodium nucleinate" exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (Jukic et al., 2012).</li>
<li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (Jukic et al., 2011).</li>
</ul>
<li><strong>Tetrahydrophthalazine derivative "sodium nucleinate" exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (Jukic et al., 2012).</li>
<li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (Jukic et al., 2011).</li>
</ul>
Biochem/physiol Actions
Sodium nucleinate (SN) serves as an immunomodulatory substance, that possess anti-inflammatory effects.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Tetrahydrophthalazine Derivative
Jukic T, et al.
Collegium Antropologicum, 36(2), 409-412 (2012)
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