Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

537721

Sigma-Aldrich

3-Methyl-2-butanone

99%

Synonym(s):

Isopropyl methyl ketone, Methyl isopropyl ketone

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)2CHCOCH3
CAS Number:
563-80-4
Molecular Weight:
86.13
Beilstein:
1071238
EC Number:
209-264-3
MDL number:
MFCD00008919
UNSPSC Code:
12352115
PubChem Substance ID:
329757993
NACRES:
NA.21

Assay

99%

form

liquid

expl. lim.

0.34-6.3 %

refractive index

n20/D 1.388 (lit.)

bp

94-95 °C (lit.)

mp

−92 °C (lit.)

solubility

water: soluble 8.21 g/L at 20 °C

density

0.805 g/mL at 25 °C (lit.)

SMILES string

CC(C)C(C)=O

InChI

1S/C5H10O/c1-4(2)5(3)6/h4H,1-3H3

InChI key

SYBYTAAJFKOIEJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

3-Methyl-2-butanone (Methyl isopropyl ketone, MIPK, isopropyl methyl ketone), an aliphatic ketone, is a volatile organic compound. Photodegradation of MIPK in gas-phase has been reported. Asymmetric hydrogenation of MIPK with high enantioselectivity in the presence of Rh-PennPhos (rhodium-P,P′-1,2-phenylenebis(endo-2,5-dialkyl-7-phosphabicyclo[2.2.1]heptane) complex has been reported.

Application

3-Methyl-2-butanone may be used to prepare (R)-3-methyl-2-butanol via asymmetric hydrogenation in the presence of a wool-Pd complex.

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H225

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

26.6 °F - closed cup

Flash Point(C)

-3 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Photocatalytic destruction of VOCs in the gas-phase using titanium dioxide.
Alberici RM and Jardim WF.
Applied Catalysis. B, Environmental, 14(1), 55-68 (1997)
Highly enantioselective hydrogenation of simple ketones catalyzed by a Rh-PennPhos complex.
Jiang Q, et al.
Angewandte Chemie (International Edition in English), 37(8), 1100-1103 (1998)
Catalytic behavior of a Wool-Pd complex in asymmetric hydrogenation of diacetone alcohol and 3-methyl-2-butanone.
Yin MO, et al.
J. Mol. Catal. A: Chem., 147(1), 89-92 (1999)
Sami Sajjadifar et al.
Molecules (Basel, Switzerland), 15(4), 2491-2498 (2010-04-30)
Methyl indolenines (4a-c) and(5a-c) were prepared in high yield by a Fischer indole synthesis reaction of o,m-tolylhydrazine hydrochlorides (1a-b) with isopropyl methyl ketone (2) and 2-methylcyclohexanone (3) in acetic acid at room temperature. o,p- Nitrophenylhydrazines (1c-d) were reacted with 2-methylcyclohexanone
E M Gagan et al.
Archives of environmental contamination and toxicology, 52(3), 283-293 (2007-01-27)
Frequently the toxicity of an organic chemical mixture is close to dose-additive, even when the agents are thought to induce toxicity at different molecular sites of action. These findings appear to conflict with the hypothesis that a strictly dose-additive combined
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service