198218

Patent Blue VF

Dye content 50 %

• Synonym(s): Acid Blue 1, Sulfan Blue
• Empirical Formula (Hill Notation): C₂₇H₃₁N₂NaO₆S₂
• CAS Number: 129-17-9
• Molecular Weight: 566.66
• Colour Index Number: 42045
• EC Number: 204-934-1
• MDL number: MFCD00012119
• UNSPSC Code: 12171500
• PubChem Substance ID: 24851867
• NACRES: NA.47

Properties

• form: powder
• Quality Level: 200
• composition: Dye content, 50%
• solubility: H₂O: 1 mg/mL
• λmax: 635 nm (2nd); -410 nm
• ε (extinction coefficient): ≥50000 at 635-641 nm in H₂O; ≥5300 at 408-414 nm in H₂O; ≥7500 at 308-314 nm in H₂O
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Na+].CCN(CC)c1ccc(cc1)\C(=C2/C=CC(\C=C2)=[N+](\CC)CC)c3ccc(cc3S([O-])(=O)=O)S([O-])(=O)=O
• InChI: 1S/C27H32N2O6S2.Na/c1-5-28(6-2)22-13-9-20(10-14-22)27(21-11-15-23(16-12-21)29(7-3)8-4)25-18-17-24(36(30,31)32)19-26(25)37(33,34)35;/h9-19H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
• InChI key: SJEYSFABYSGQBG-UHFFFAOYSA-M

Description

Application

Patent Blue VF has been used:

• in combination with 99mTc phytate to detect sentinel lymph node (SLN) in early stage cervical cancer patients.
• to detect heat shock protein (HSP) gp96 induced draining lymph nodes (LNs) in mice.
• to detect the effect of Asn-Gly-Arg (NGR)-tumor necrosis factor (TNF) on tumor perfusion in murine model.

Biochem/physiol Actions

Patent Blue VF dye is a violet colored powder. It has been used in cosmetic coloring.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves