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M7780

Supelco

3-Methylhistamine dihydrochloride

analytical standard

Synonym(s):

3-Methyl-4-(β-aminoethyl)imidazole

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About This Item

Empirical Formula (Hill Notation):
C6H11N3 · 2HCl
CAS Number:
36475-47-5
Molecular Weight:
198.09
MDL number:
MFCD00037002
UNSPSC Code:
41116107
PubChem Substance ID:
329817916
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.Cl.Cn1cncc1CCN

InChI

1S/C6H11N3.2ClH/c1-9-5-8-4-6(9)2-3-7;;/h4-5H,2-3,7H2,1H3;2*1H

InChI key

KWEIZIDNCJBKIY-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000380947
0000358652
0000348883
0000322195
0000358652

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J G Gerber et al.
Gastroenterology, 102(2), 403-408 (1992-02-01)
The effect of short-term intragastric arterial infusion of pentagastrin and methacholine on histamine and N tau-methyl histamine secretory rates was evaluated in mongrel dogs in vivo. Doses of pentagastrin and methacholine were chosen that stimulate gastric acid secretion equivalently. Histamine
A Sasse et al.
Journal of medicinal chemistry, 43(17), 3335-3343 (2000-09-01)
Histamine H(3)-receptor antagonists of the proxifan series are described. The novel compounds possess a 4-(3-(phenoxy)propyl)-1H-imidazole structure and various functional groups, e.g., an oxime moiety, on the phenyl ring. Synthesis of the novel compounds and X-ray crystallography of one highly potent
J C Fitzpatrick et al.
The Journal of surgical research, 49(4), 293-297 (1990-10-01)
Carcinine (beta-alanylhistamine) is an imidazole dipeptide that exists in mammalian hearts, increases cardiac contractility, and is metabolically linked to carnosine (beta-alanylhistidine), a non-mast cell histidine and histamine precursor during stress. We have previously shown that tissue carnosine levels are regulated
E Oosting et al.
Agents and actions, 33(1-2), 215-217 (1991-05-01)
A newly developed radioimmunoassay (RIA, Y) for the determination of urinary N tau-methylhistamine concentrations was correlated with gas chromatography mass spectrometry (GCMS, X). In 34 urine samples, with histamine and N tau-methylhistamine levels within our reference values, the correlation was:
S Murray et al.
Journal of chromatography, 567(2), 289-298 (1991-07-05)
An assay has been developed for N tau-methylhistamine, a major metabolite of the autocoid histamine, based on gas chromatography-electron-capture negative-ion chemical ionisation mass spectrometry. N tau-Methylhistamine was extracted from urine by cation-exchange chromatography and converted to its di-(3,5-bistrifluoromethylbenzoyl) derivative. The
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