AB1570
Anti-GABA Transporter-1 Antibody, CT (a.a. 588-599)
Chemicon®, from rabbit
Synonym(s):
GAT-1
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
monkey, feline, rat, human, mouse, rabbit
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
suitability
not suitable for Western blot
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SLC6A1(6529)
Specificity
GABA Transporter-1 (GAT-1), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.
Immunogen
Epitope: C-terminus (a.a. 588-599)
Rat GAT-1, C-terminus (aa 588-599)
Application
Anti-GABA Transporter-1 Antibody, C-terminus (a.a. 588-599) is an antibody against GABA Transporter-1 for use in IH.
Immunohistochemistry: 1:500-1:750 on 4% paraformaldehyde fixed or 4% paraformaldehyde and 0.2% glutaraldehyde fixed tissue. It is recommended that the antibody be diluted in PBS containing 10% normal goat serum and 0.5% Triton X-100. AB1570 has been used for both light and electron microscopic studies of rat retina, cortex and hippocampus.
Note: AB1570 is not recommended for Western blot use. See AB1570W.
Optimal working dilutions must be determined by the end user.
Note: AB1570 is not recommended for Western blot use. See AB1570W.
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified antibody. Lyophilized from in 0.1 M PBS with 1% BSA and 0.1% sodium azide. Reconstitute with 100 μL of sterile distilled water.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Lu Pu et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 818451-818451 (2013-02-01)
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation. Here we investigated regulation of GABA transporter GAT1 by δOR in rats and in
Pericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.
Blazquez-Llorca, L; Garcia-Marin, V; Defelipe, J
Frontiers in Neuroanatomy null
Muhamed N H Eeza et al.
Journal of Alzheimer's disease : JAD, 81(2), 797-808 (2021-04-13)
Circadian rhythm disturbance is commonly observed in Alzheimer's disease (AD). In mammals, these rhythms are orchestrated by the superchiasmatic nucleus (SCN). Our previous study in the Tg2576 AD mouse model suggests that inflammatory responses, most likely manifested by low GABA
Constantino Sotelo
The Journal of comparative neurology, 506(2), 240-262 (2007-11-21)
The acquisition of the dynamic balance between excitation and inhibition in developing Purkinje cells, necessary for their proper function, is analyzed. Newborn (P0) mouse cerebellum contains glutamatergic (VGLUT2-IR) and gamma-aminobutyric acid (GABA)-ergic (VIAAT-IR) axons. The former prevail and belong to
Xinjun Wang et al.
The Journal of physiology, 592(19), 4257-4276 (2014-08-03)
GABAergic terminals of chandelier cells exclusively innervate the axon initial segment (AIS) of excitatory neurons. Although the anatomy of these synapses has been well-studied in several brain areas, relatively little is known about their physiological properties. Using vesicular γ-aminobutyric acid
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