S5071

SFK1

≥98% (HPLC), solid

• Synonym(s): Cyclohexylmethyl 4-[imino(octylamino)methyl]benzoate hydrochloride, Suppressor of FK-506 1
• Empirical Formula (Hill Notation): C₂₃H₃₇ClN₂O₂
• CAS Number: 678997-25-6
• Molecular Weight: 409.01
• MDL number: MFCD06412465
• UNSPSC Code: 51111800
• PubChem Substance ID: 24724612
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• solubility: DMSO: 12 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cl[H].CCCCCCCCNC(=N)c1ccc(cc1)C(=O)OCC2CCCCC2
• InChI: 1S/C23H36N2O2.ClH/c1-2-3-4-5-6-10-17-25-22(24)20-13-15-21(16-14-20)23(26)27-18-19-11-8-7-9-12-19;/h13-16,19H,2-12,17-18H2,1H3,(H2,24,25);1H
• InChI key: URYYYIJUCLTKBY-UHFFFAOYSA-N

Description

Application

SFK1 may be used in cell signaling studies.

Biochem/physiol Actions

SFK1 interacts directly with yeast mitochodria. Induces cell death in low salt conditions and suppresses the ability of FK506 to inhibit cell growth in the presence of high levels of NaCl.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H318
• Precautionary Statements: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves