A8251

Acriflavine hydrochloride

Powder

• Synonym(s): 3,6-Diamino-10-methylacridinium chloride hydrochloride, Euflavine
• CAS Number: 8063-24-9
• Beilstein: 6265525
• MDL number: MFCD00069039
• UNSPSC Code: 12171500
• PubChem Substance ID: 24891216
• NACRES: NA.47

Properties

• product name: Acriflavine hydrochloride, fluorescent dye
• Quality Level: 200
• form: powder
• composition: Acriflavine HCL content, 10-50% ; Proflavine HCL, 25-70%
• color: faint brown to brown, and Orange to Dark Orange and Red to Very Dark Red
• mp: 260 °C (dec.) (lit.)
• solubility: H₂O: 1 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Cl-].Cl[H].Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]4c5cc(N)ccc5cc6ccc(N)cc46
• InChI: 1S/C14H13N3.C13H11N3.3ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;;;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;3*1H
• InChI key: MKLTXAHQKDVBLY-UHFFFAOYSA-N

Description

Application

In living mice, acriflavine hydrochloride has been used in the confocal laser endomicroscopy to check the crypt structure in mucosa. It has also been used in Neurospora strain selection by checking the acriflavine resistance.

Biochem/physiol Actions

Acriflavine hydrochloride is a fluorescent dye. It is used as a topical contrast agent. It mainly stains nuclei and is applied to tissues before microscopy.

Other Notes

A mixture of 3,6-diamino-10-methylacridinium (acriflavin) and 3,6-diaminoacridine (proflavin)

Safety Information

• Pictograms: GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302,H318,H411
• Precautionary Statements: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P391
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves