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32173

Supelco

Ipronidazole

VETRANAL®, analytical standard

Synonym(s):

1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole, 2-Isopropyl-1-methyl-5-nitroimidazol, NSC 109212, Ro 07-1554

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About This Item

Empirical Formula (Hill Notation):
C7H11N3O2
CAS Number:
Molecular Weight:
169.18
Beilstein:
744577
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

InChI

1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3

InChI key

NTAFJUSDNOSFFY-UHFFFAOYSA-N

General description

Ipronidazole is a veterinary drug, which is widely used in controlling histomoniasis in turkeys.

Application

Ipronidazole may be used as a reference standard in the determination of ipronidazole in tissue samples using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC) and thermospray tandem mass spectrometry (HPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Determination of ipronidazole and its principal metabolite in turkey skin and muscle by combined gas chromatography-negative chemical ionization mass spectrometry-stable isotope dilution.
W A Garland et al.
Journal of agricultural and food chemistry, 28(2), 273-277 (1980-03-01)
J E Roybal et al.
Journal - Association of Official Analytical Chemists, 70(4), 626-630 (1987-07-01)
A simple and rapid method is described for the determination of dimetridazole (DMZ) and ipronidazole (IPR) in swine feeds at various levels (0.11-110 ppm). The drugs are released from feed by prewetting with a buffer, followed by extraction with either
Identification of dimetridazole, ipronidazole, and their alcohol metabolites in turkey tissues by thermospray tandem mass spectrometry.
Matusik EJ, et al.
Journal of Agricultural and Food Chemistry, 40(3), 439-443 (1992)
W J Morris et al.
Journal - Association of Official Analytical Chemists, 70(4), 630-634 (1987-07-01)
Extracts from 4 types of swine feed containing 0.11 ppm each of dimetridazole (DMZ) and ipronidazole (IPR) were analyzed by capillary gas chromatography/mass spectrometry (GC/MS) using multiple ion detection (MID) techniques. We demonstrate in this paper that the quantitative results
S Skirrow et al.
Journal of the American Veterinary Medical Association, 187(4), 405-407 (1985-08-15)
Preputial smegma samples from 195 beef bulls were collected repeatedly and cultured for Tritrichomonas foetus. Seventy-five (38.5%) of these bulls were positive for trichomonads on at least 1 culture. Sensitivity of the culture procedure (number of positive cultures/number of total

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