03-0185-00
SMC® Human Total Tau High Sensitivity Immunoassay Kit
Synonym(s):
Microtubile-associated protein tau immunoassay kit, Neurofibrillary tangle protein immunoassay kit, Tau Single Molecule Counting Kit, Tau ultra-sensitive immunoassay
About This Item
species reactivity
human
manufacturer/tradename
SMC®
assay range
sensitivity: 4.69 pg/mL
((lower limit of quantification))
inter-assay cv: ≤4%
intra-assay cv: ≤8%
(Intra-assay CV n=5; Inter-assay n=3)
Related Categories
General description
The SMC® Human Total Tau High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2) The Erenna and TM="SMCxPRO"] immunoassay systems detect analytes using Single Molecule Counting SMC® technology.
Specificity
- Non Human Primate – 50%
- Mouse – 100%
- Rat – 100%
- Canine – 100%
- Feline – 75%
Application
This new streamline kit has the following features:
- Improved options for sample prep and incubation
- Lyophilization protein standard for uniform shipping and storage condition
- Increased reagent volumes to accommodate automation
- Able to achieve assay specifications on both SMCxPRO® and Erenna.
Research Category:
Neuroscience
neurological
Research Sub-Category:
Alzheimer′s Disease
Aging, Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
Components
- Assay Buffer
- Total Tau Coated Beads
- Standard Diluent
- Total Tau Detection Antibody
- Total Tau Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
Specifications
Minimum of 4 plasma samples spiked with average recovery of 82% with a range of 76-88%
Minimum of 5 CSF samples spiked with average recovery of 91% with a range of 85-106%
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
Target Organs
Respiratory Tract
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificates of Analysis (COA)
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