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409014

Sigma-Aldrich

Poly(diallyldimethylammonium chloride) solution

20 wt. % in H2O

Synonym(s):

PDADMAC

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About This Item

Linear Formula:
(C8H16ClN)n
CAS Number:
26062-79-3
MDL number:
MFCD00192409
UNSPSC Code:
12162002
NACRES:
NA.23

form

viscous liquid

concentration

20 wt. % in H2O

refractive index

n20/D 1.375

viscosity

60-180 cP(25 °C)

density

1.04 g/mL at 25 °C

InChI

1S/C8H16N.ClH/c1-5-7-9(3,4)8-6-2;/h5-6H,1-2,7-8H2,3-4H3;1H/q+1;/p-1

InChI key

GQOKIYDTHHZSCJ-UHFFFAOYSA-M

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General description

Poly(diallyldimethylammonium chloride) solution (PDADMAC) is a cationic polyelectrolyte that is widely utilized as a flocculant. It is prepared by the radical polymerization of diallyldimethylammonium chloride (DADMAC) in presence of a catalyst in the form of an organic peroxide.

Application

PDADMAC can be used as an electrolytic solution in combination with mesoporous silica to form a responsive carrier system for potential usage in drug delivery. It can be also be coated on gold nanorods to enhance the cellular uptake in biomedical systems. It is used in the surface modification of indium tin oxide (ITO) substrate which may be used in chemical sensors or biosensor based applications.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Synthesis and use of PolyDADMAC for water purification
Biennial Conference of the Water Institute of Southern Africa, Durban, South Africa, 46(8), 2584-2594 (2002)
Polyelectrolyte multilayer as matrix for electrochemical deposition of gold clusters: toward super-hydrophobic surface
Zhang X, et al.
Journal of the American Chemical Society, 126(10), 3064-3065 (2004)
Synthesis and solution properties of poly (N-isopropylacrylamide-co-diallyldimethylammonium chloride)
Deng Y and Pelton R
Macromolecules, 28(13), 4617-4621 (1995)
Urszula Bazylińska et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(2), 406-420 (2012-07-17)
There is great clinical interest in developing novel nanocarriers for hydrophobic cyanine dyes used as photosensitizing agents in photodynamic therapy (PDT). In the present study we have employed nanoemulsion-templated oil-core multilayer nanocapsules as robust nanocarriers for a cyanine-type photosensitizer IR-786.
Cédric Amorosi et al.
Colloids and surfaces. B, Biointerfaces, 97, 124-131 (2012-05-23)
Compact and linearly growing polyelectrolyte multilayer films have been used to suppress desorption of drugs, nanoparticles or proteins from underlying polyelectrolyte multilayer films as well as to significantly change their mechanical properties. The polyelectrolyte based capping layers are however cumbersome
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Articles

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

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