Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

P9271

Sigma-Aldrich

α-(4-Pyridyl N-oxide)-N-tert-butylnitrone

~95%

Synonym(s):

N-(4-Pyridylmethylene)-tert-butylamine N,N′-dioxide, N-tert-Butyl-α-(4-pyridyl)nitrone N′-oxide, POBN

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C10H14N2O2
CAS Number:
66893-81-0
Molecular Weight:
194.23
Beilstein:
1453764
EC Number:
266-512-3
MDL number:
MFCD00041022
UNSPSC Code:
12352100
PubChem Substance ID:
24899024
NACRES:
NA.22

Assay

~95%

form

crystals

mp

183-185 °C (lit.)

storage temp.

room temp

SMILES string

CC(C)(C)\[N+]([O-])=C/c1cc[n+]([O-])cc1

InChI

1S/C10H14N2O2/c1-10(2,3)12(14)8-9-4-6-11(13)7-5-9/h4-8H,1-3H3/b12-8+

InChI key

RNRMWTCECDHNQU-XYOKQWHBSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hitoshi Maeda et al.
The Journal of pharmacology and experimental therapeutics, 352(2), 244-257 (2014-11-16)
Since reactive oxygen species (ROS) derived from Kupffer cells (KC), especially CD68(+) KC, play a key role in the induction of hepatic oxidative stress and injuries, we developed a polythiolated- and mannosylated human serum albumin (SH-Man-HSA), which functions as a
Hua Yang et al.
Environmental science and pollution research international, 22(14), 10882-10889 (2015-03-17)
Low-cost and environmentally friendly mediators could facilitate the application of laccase (EC 1.10.3.2) in variant biotechnological processes. Acetylacetone (AA) represents an inexpensive and low toxic small molecular diketone that has been proven as an effective mediator for laccase in free
Eduardo Henrique Silva Sousa et al.
Journal of inorganic biochemistry, 140, 236-244 (2014-09-06)
Tuberculosis has re-emerged as a worldwide threat, which has motivated the development of new drugs. The antituberculosis complex Na3[Fe(CN)5(isoniazid)] (IQG607) in particular is of interest on account of its ability to overcome resistance. IQG607 has the potential for redox-mediated-activation, in
Thiago C Genaro-Mattos et al.
Biochemistry, 54(18), 2841-2850 (2015-04-14)
Lipid peroxidation is a well-known process that has been implicated in many diseases. Recent evidence has shown that mitochondrial cholesterol levels are increased under specific conditions, making it an important target for peroxidation inside the mitochondria. Cholesterol peroxidation generates, as

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service