53588

Homopiperazine-1,4-bis(2-ethanesulfonic acid)

• Synonym(s): Hexahydro-1H-1,4-diazepine-1,4-bis(2-ethanesulfonic acid), Homo-PIPES
• Empirical Formula (Hill Notation): C₉H₂₀N₂O₆S₂
• CAS Number: 202185-84-0
• Molecular Weight: 316.39
• MDL number: MFCD00467737
• UNSPSC Code: 12352100
• PubChem Substance ID: 57651422
• NACRES: NA.22

Properties

• form: solid
• impurities: ≤5% water
• SMILES string: OS(=O)(=O)CCN1CCCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C9H20N2O6S2/c12-18(13,14)8-6-10-2-1-3-11(5-4-10)7-9-19(15,16)17/h1-9H2,(H,12,13,14)(H,15,16,17)
• InChI key: QZTMPPUJIVQNKS-UHFFFAOYSA-N

Description

General description

Homopiperazine-1,4-bis(2-ethanesulfonic acid) is used as a buffer in experiments involving plant cells at low pH.

Application

• Evaluation of buffers toxicity in plant cells: Homopiperazine-1,4-bis(2-ethanesulfonic acid) was evaluated for its suitability as a buffer in tobacco cell studies at low pH, highlighting its low toxicity and effectiveness in maintaining stable pH environments crucial for plant cell biology experiments (Borgo, 2017).
• Proteomic analysis under stress conditions: This buffer was used in maintaining pH during the proteomic analysis of radicles from seeds treated with aluminum, showcasing its utility in complex biological assays and environmental stress studies (Okekeogbu et al., 2014).

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H312,H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Dermal - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves