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Reactive electrospinning of degradable poly(oligoethylene glycol methacrylate)-based nanofibrous hydrogel networks.

Chemical communications (Cambridge, England) (2015-12-10)
Fei Xu, Heather Sheardown, Todd Hoare
RÉSUMÉ

A direct, all-aqueous electrospinning method for fabricating degradable nanofibrous hydrogel networks is reported in which hydrazide and aldehyde-functionalized poly(oligoethylene glycol methacrylate) (POEGMA) polymers are simultaneously electrospun and cross-linked. The resulting networks are spatially well-defined, mechanically stable (both dry and wet), and offer extremely fast swelling responses, suggesting potential utility as smart hydrogels and tunable tissue engineering matrices.

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Description du produit

Sigma-Aldrich
Poly(OEGMA), hydrazide functionalized, 25 wt% solution in water
Sigma-Aldrich
Poly(M(EO)2MA:Poly(OEGMA), (90:10), aldehyde functionalized, 25 wt% solution in water
Sigma-Aldrich
Poly(M(EO)2MA:Poly(OEGMA) 90:10, hydrazide functionalized, 25 wt. % (solution in water)