- Comparative pharmacokinetics of six major bioactive components in normal and type 2 diabetic rats after oral administration of Sanhuang Xiexin Decoction extracts by UPLC-TQ MS/MS.
Comparative pharmacokinetics of six major bioactive components in normal and type 2 diabetic rats after oral administration of Sanhuang Xiexin Decoction extracts by UPLC-TQ MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2017-08-02)
Xiao-Yan Wei, Jin-Hua Tao, Xiang Cui, Shu Jiang, Da-Wei Qian, Jin-Ao Duan
PMID28756356
RÉSUMÉ
A rapid, sensitive, and selective UPLC-TQ-MS/MS method was established and validated for the determination and pharmacokinetic investigation of rhein, coptisine, berberine, palmatine, baicalin and wogonoside from Sanhuang Xiexin Decoction (SXD) extracts. A Waters BEH C
MATÉRIAUX