- Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology.
Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology.
Journal of pharmacological sciences (2017-03-02)
Suchitra Matsukura, Yuji Nakamura, Xin Cao, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando, Hiroshi Yamazaki, Atsushi Sugiyama
PMID28245963
RÉSUMÉ
We pharmacologically characterized microminipigs as an in vivo experimental model by assessing cardiovascular effects of pilsicainide, verapamil and E-4031, which can preferentially inhibit cardiac Na
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