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Merck

Asterixis related to gabapentin intake: a case report and review.

Postgraduate medicine (2013-10-12)
Mervat Wahba, Olga Waln
RÉSUMÉ

Asterixis has been reported as a side effect of toxic and metabolic abnormalities. The current literature contains very little evidence of gabapentin-related neurotoxicity. Our observations reveal that neurotoxic side effects of gabapentin use may be seen even when dose adjustments are made for patients with mild-to-moderate renal dysfunction. Clinical vigilance for possible neurotoxic effects of gabapentin therapy in patients with renal dysfunction is warranted.

MATÉRIAUX
Référence du produit
Marque
Description du produit

USP
Gabapentin, United States Pharmacopeia (USP) Reference Standard
Supelco
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Gabapentin, solid
Supelco
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Gabapentin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material