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  • A reversible fluorescence probe based on Se-BODIPY for the redox cycle between HClO oxidative stress and H2S repair in living cells.

A reversible fluorescence probe based on Se-BODIPY for the redox cycle between HClO oxidative stress and H2S repair in living cells.

Chemical communications (Cambridge, England) (2012-12-22)
Bingshuai Wang, Peng Li, Fabiao Yu, Ping Song, Xiaofei Sun, Songqiu Yang, Zhangrong Lou, Keli Han
RÉSUMÉ

We have developed a new reversible fluorescence probe MPhSe-BOD for the redox cycle process between hypochlorous acid and hydrogen sulfide in solution and in living cells. Confocal microscopy imaging using RAW264.7 cell lines shows that the probe has good cell membrane permeability, and can monitor intracellular HClO/H(2)S redox cycles continuously.

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Sigma-Aldrich
Porphobilinogen, powder