Accéder au contenu
Merck

Conformational modulation of Ant-Pro oligomers using chirality alteration of proline residues.

Organic & biomolecular chemistry (2012-09-25)
Sangram S Kale, Amol S Kotmale, Achintya Kumar Dutta, Sourav Pal, P R Rajamohanan, Gangadhar J Sanjayan
RÉSUMÉ

Structural modulation of Ant-Pro (anthranilic acid-proline) oligomers has been carried out by chirality alteration of the proline residues. The results suggest that the chirality altered oligomers show well-defined helical conformation featuring nine-membered hydrogen bonding interactions - without compromising conformational rigidity.

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
Anthranilic acid, reagent grade, ≥98%
Sigma-Aldrich
Anthranilic acid, puriss. p.a., ≥99.5% (T)