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  • Genotypic resistance testing creates new treatment challenges: two cases of oxacillin-susceptible methicillin-resistant Staphylococcus aureus.

Genotypic resistance testing creates new treatment challenges: two cases of oxacillin-susceptible methicillin-resistant Staphylococcus aureus.

Journal of clinical microbiology (2012-09-21)
Katie A Sharff, Stefan Monecke, Sarah Slaughter, Graeme Forrest, Chris Pfeiffer, Ralf Ehricht, Margret Oethinger
RÉSUMÉ

Oxacillin-susceptible, mecA-positive Staphylococcus aureus isolates create a treatment challenge for the clinician. In this article, we describe two cases of bacteremia from isolates that carried the mecA gene but were susceptible to oxacillin (oxacillin-susceptible methicillin-resistant S. aureus [OS-MRSA]). DNA microarray analysis was used to characterize these isolates as a mecA-positive, clonal complex 5, pediatric strain and a mecA-positive, clonal complex 8, USA300 strain.

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Sigma-Aldrich
Oxacillin sodium salt, 815-950 μg/mg (Oxacillin)
Supelco
Oxacilline sodium salt hydrate, VETRANAL®, analytical standard