- Asymmetric synthesis of alpha-tocopherol.
Asymmetric synthesis of alpha-tocopherol.
Chemistry (Weinheim an der Bergstrasse, Germany) (2009-12-17)
Urs Hengartner, Antoinette Chougnet, Kegang Liu, Wolf-D Woggon
PMID20013765
RÉSUMÉ
Alpha-tocopherol was synthesized from a chiral intermediate alpha-hydroxy ester by means of two ring-closing methods to yield the chromanol in 94% diastereomeric excess.
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