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  • Mild electrophilic trifluoromethylation of secondary and primary aryl- and alkylphosphines using hypervalent iodine(iii)-CF(3) reagents.

Mild electrophilic trifluoromethylation of secondary and primary aryl- and alkylphosphines using hypervalent iodine(iii)-CF(3) reagents.

Chemical communications (Cambridge, England) (2008-03-21)
Patrick Eisenberger, Iris Kieltsch, Nicolas Armanino, Antonio Togni
RÉSUMÉ

A direct, mild and efficient trifluoromethylation of primary and secondary phosphines is achieved with easily accessible, cheap hypervalent iodine compounds acting as electrophilic CF(3)-transfer reagents.

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Sigma-Aldrich
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, 95%