SAB4503810

Anti-phospho-CDC25B (pSer³²³) antibody produced in rabbit

affinity isolated antibody

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 64 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P30305
• Numéro d'accès UniProt: P30305
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pSer323)
• Informations sur le gène: human ... CDC25B(994)

Description

Description générale

CDC25B (cell division cycle 25B), a short half-life protein belongs to the dual-specificity CDC25 phosphatases family. It is located on human chromosome 20p. The protein is upregulated in late G2 of the cell cycle.

Immunogène

The antiserum was produced against synthesized peptide derived from human CDC25B around the phosphorylation site of Ser323.

Immunogen Range: 289-338

Actions biochimiques/physiologiques

The expression of CDC25B (cell division cycle 25B) can be considered as a prognostic marker in the pathogenesis of retinoblastoma. It helps to dephosphorylate CDK1 (cyclin-dependent kinase 1) and ERK1/2 (extracellular signal-regulated kinase 1/2). It controls the cell cycle.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable